{"schema_version":"alpha-profile-public-v1","slug":"jeffrey-p-castelli","canonical_url":"https://registry.alpha.ac/people/jeffrey-p-castelli","as_of":"2026-11-14T11:51:49.898909+00:00","published_at":"2026-09-02T04:20:44.357425+00:00","last_reviewed_at":"2026-05-15T00:21:43.368+00:00","identity":{"display_name":"Jeffrey P. Castelli","headshot_url":null,"headshot_media":null,"profile_kind":"executive","role_tags":["executive"],"current_role":null,"photo_match":null},"assurance":{"is_claimed":false,"status":"unverified","assurance_level":null,"method":null,"verified_at":null,"expires_at":null},"claiming":{"eligible":true,"label":"Is this you? Claim your Alpha Profile","claim_url":"https://terminal.alpha.ac/claim-profile?person=jeffrey-p-castelli","suggest_edit_label":"Suggest an edit","suggest_edit_url":"https://terminal.alpha.ac/claim-profile?person=jeffrey-p-castelli&mode=suggest","canonical_record_will_be_reused":true,"canonical_facts_owner_controlled":false},"presentation":{"schema_version":"alpha-profile-presentation-v1","state":"alpha_editorial","version":0,"published_at":null,"headline":null,"headline_evidence":null,"location":null,"photo":null,"cover":null,"about":["Jeffrey Castelli, Ph.D., has served as Chief Development Officer since May 2020 and has been with Amicus since July 2005. He has over 20 years of experience in the Biotech and Orphan Drug industry, providing strategic leadership across all R&D activities including Regulatory, Science, Clinical Research, Clinical Operations, and Medical Affairs."],"links":[],"sources":[],"featured":[],"competencies":[],"board_preferences":null,"board_service":[],"experience":[],"education":[],"credentials":[],"section_order":null,"hidden_sections":[],"limitations":["Presentation fields do not alter independently verified Alpha Profile facts.","Owner-supplied résumé records retain their field-level evidence state.","Only confirmed company_person_roles with public evidence. Website governed_site_fallback rows are not invented. about/links are stored people.profile_summary/bio and linkedin_url only. Dates stay undisclosed when the role has no start_date. SoFi Bank is not SoFi Technologies."]},"presentation_authority":"confirmed_company_person_roles","roles":[],"claims":[{"claim_type":"ai_expertise","claim_value":{"detail":"Jeffrey Castelli, Ph.D., has served as Chief Development Officer since May 2020 and has been with Amicus since July 2005, with over 20 years of experience in biotech and orphan drug development. He provides strategic leadership across all R&D activities including regulatory, clinical research, and medical affairs.","ai_expertise":false},"claim_text":"SEC-derived executive row classified AI expertise as False.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-03T15:43:25.702885+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD executive roster source","source_type":"sec_filing","source_tier":3,"source_url":null,"published_at":null,"last_checked_at":"2026-05-03T15:42:45.317063+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"ai_governance_relevance","claim_value":{"reasons":["biography_scope_ai_governance_adjacent"],"relevant":true},"claim_text":"AI-governance relevance classified as True from role/title and SEC-derived executive context.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-03T15:43:25.702885+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD executive roster source","source_type":"sec_filing","source_tier":3,"source_url":null,"published_at":null,"last_checked_at":"2026-05-03T15:42:45.317063+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"ai_ml_experience","claim_value":false,"claim_text":"Executive extraction classified AI/ML experience for Jeffrey P. Castelli as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T00:21:43.586165+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD 10-K executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1178879/000117887926000005/fold-20251231.htm","published_at":"2026-02-20T00:00:00+00:00","last_checked_at":"2026-05-15T00:21:43.431364+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"cybersecurity_experience","claim_value":false,"claim_text":"Executive extraction classified cybersecurity experience for Jeffrey P. Castelli as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T00:21:43.621536+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD 10-K executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1178879/000117887926000005/fold-20251231.htm","published_at":"2026-02-20T00:00:00+00:00","last_checked_at":"2026-05-15T00:21:43.431364+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_company","claim_value":"Amicus Therapeutics","claim_text":"Jeffrey P. Castelli is associated with Amicus Therapeutics.","claim_state":"verified","valid_from":"2026-02-20","valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T00:21:43.567711+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD 10-K executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1178879/000117887926000005/fold-20251231.htm","published_at":"2026-02-20T00:00:00+00:00","last_checked_at":"2026-05-15T00:21:43.431364+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_company","claim_value":{"ticker":"FOLD","company":"Amicus Therapeutics"},"claim_text":"Jeffrey P. Castelli is associated with Amicus Therapeutics.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-03T15:43:25.702885+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD executive roster source","source_type":"sec_filing","source_tier":3,"source_url":null,"published_at":null,"last_checked_at":"2026-05-03T15:42:45.317063+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_function","claim_value":{"role_family":"other_executive","role_type_normalized":"other_executive"},"claim_text":"Jeffrey P. Castelli maps to the other executive executive function.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-03T15:43:25.702885+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD executive roster source","source_type":"sec_filing","source_tier":3,"source_url":null,"published_at":null,"last_checked_at":"2026-05-03T15:42:45.317063+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_title","claim_value":"Chief Development Officer","claim_text":"Jeffrey P. Castelli is listed as Chief Development Officer at Amicus Therapeutics.","claim_state":"verified","valid_from":"2026-02-20","valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T00:21:43.548796+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD 10-K executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1178879/000117887926000005/fold-20251231.htm","published_at":"2026-02-20T00:00:00+00:00","last_checked_at":"2026-05-15T00:21:43.431364+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_title","claim_value":{"title":"Chief Development Officer","role_type_normalized":"other_executive"},"claim_text":"Jeffrey P. Castelli is listed as Chief Development Officer at Amicus Therapeutics.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-03T15:43:25.702885+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD executive roster source","source_type":"sec_filing","source_tier":3,"source_url":null,"published_at":null,"last_checked_at":"2026-05-03T15:42:45.317063+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"technology_background","claim_value":false,"claim_text":"Executive extraction classified technology background for Jeffrey P. Castelli as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T00:21:43.604397+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"FOLD 10-K executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1178879/000117887926000005/fold-20251231.htm","published_at":"2026-02-20T00:00:00+00:00","last_checked_at":"2026-05-15T00:21:43.431364+00:00","relation":"supports","excerpt_locator":null}]}],"network":{"schema_version":"alpha-profile-network-public-v1","relationships":[],"relationship_pathfinding":false,"authentication_prompt":"Sign in to see how you're connected.","limitations":["Representative factual associations only.","Shared contexts do not assert personal acquaintance.","Anonymous graph traversal is not available."]},"permissions":{"classification":"open_public_projection","public_retrieval":true,"agent_retrieval":true,"redistribution":false,"model_training":false,"relationship_pathfinding":false,"direct_contact":false},"limitations":["Only permissioned public claims and evidence are included.","Absence of a claim is not evidence that the underlying fact is false.","Public retrieval does not grant model-training or redistribution rights.","Private relationships and Council activity are excluded."],"structured_data":{"@context":"https://schema.org","@type":"ProfilePage","@id":"https://registry.alpha.ac/people/jeffrey-p-castelli#profile","url":"https://registry.alpha.ac/people/jeffrey-p-castelli","dateModified":"2026-05-15T00:21:43.368+00:00","mainEntity":{"@type":"Person","@id":"https://registry.alpha.ac/people/jeffrey-p-castelli#person","name":"Jeffrey P. Castelli","url":"https://registry.alpha.ac/people/jeffrey-p-castelli"},"isBasedOn":[{"@type":"CreativeWork","url":"https://www.sec.gov/Archives/edgar/data/1178879/000117887926000005/fold-20251231.htm","name":"FOLD 10-K executive officers"}],"mainEntityOfPage":"https://registry.alpha.ac/people/jeffrey-p-castelli"},"registry_intelligence":{"schema_version":"alpha-registry-intelligence-v1","record_version":"d751713988987e9331980363e24189ce","subject":"alpha:person:jeffrey-p-castelli","as_of":"2026-11-14T11:51:50.316766+00:00","recorded_at":"2026-11-14T11:51:50.316766+00:00","availability":"available","records":[],"next_offset":null,"limitations":["Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage."]},"trust":{"schema_version":"alpha-profile-trust-v1","verification":{"schema_version":"alpha-verification-states-v1","state":"corroborated","identity_ownership":"unclaimed","assurance_level":null,"claim_state_counts":{"source_reported":6,"corroborated":2,"alpha_verified":0,"disputed":0,"superseded":0},"derivation":"claim_states+identity_ownership","summary":"At least one published claim is corroborated by two or more public sources. Profile ownership is unclaimed."},"aggregation":{"schema_version":"alpha-claim-aggregation-v1","published_claim_count":8,"under_review_claim_count":0,"owner_supplied_claim_count":0,"evidence_record_count":2,"distinct_source_count":2,"conflicts":[],"conflict_count":0,"headline_conflict_count":0,"internal_review_conflict_count":0,"contradiction_types":[],"headline_conflict_types":[],"verification":{"schema_version":"alpha-verification-states-v1","state":"corroborated","identity_ownership":"unclaimed","assurance_level":null,"claim_state_counts":{"source_reported":6,"corroborated":2,"alpha_verified":0,"disputed":0,"superseded":0},"derivation":"claim_states+identity_ownership","summary":"At least one published claim is corroborated by two or more public sources. Profile ownership is unclaimed."},"coverage":{"schema_version":"alpha-coverage-metric-v1","published_claims":8,"corroborated_claims":2,"sources":2,"distinct_sources":2,"role_claims":0,"last_reviewed_at":"2026-05-15T00:21:43.368+00:00","observed_at":"2026-11-14T11:51:49.898909+00:00","freshness_days":183}},"rights":{"public_retrieval":"allowed","agent_retrieval":"allowed","redistribution":"not_granted","model_training":"not_granted","commercial_use":"not_specified","relationship_pathfinding":"not_granted","direct_contact":"not_granted"}},"projection":{"schema_version":"alpha-profile-projection-v5","entity":{"kind":"person","slug":"jeffrey-p-castelli","canonical_url":"https://registry.alpha.ac/people/jeffrey-p-castelli"},"publication":{"published_at":"2026-09-02T04:20:44.357425+00:00","last_reviewed_at":"2026-05-15T00:21:43.368+00:00","as_of":"2026-11-14T11:51:49.898909+00:00"},"representations":{"html":{"href":"https://registry.alpha.ac/people/jeffrey-p-castelli","media_type":"text/html"},"json":{"href":"https://registry.alpha.ac/api/public/profiles/jeffrey-p-castelli","media_type":"application/json"},"markdown":{"href":"https://registry.alpha.ac/people/jeffrey-p-castelli.md","media_type":"text/markdown"},"structured_data":{"embedded":true,"media_type":"application/ld+json"},"share_image":null},"permissions":{"public_retrieval":true,"agent_retrieval":true,"redistribution":false,"model_training":false,"relationship_pathfinding":false,"direct_contact":false}}}